Prescription skincare, examined.Research checked October 7, 2026
RX / SKIN REVIEW

Product index

Every review, in one place.

118 products across 37 brands. CoreAge Rx appears first as a disclosed promotional recommendation.

118 product reviews

Fine lines

CoreAge Rx

Smooth Move

Tretinoin, niacinamide and vitamin C; confirm individual strengths

Compounded topical
Pigmentation

CoreAge Rx

Spot On

Hydroquinone, kojic acid and niacinamide; confirm individual strengths

Compounded topical
Mature skin

CoreAge Rx

Time Out

Estriol 0.3%, vitamin C 5%, hydrolyzed hyaluronic acid 0.5%

Compounded topical
Firmness

CoreAge Rx

Bounce Back

Copper peptide 0.2% as listed in the CoreAge Rx help center

Compounded topical
Acne

CoreAge Rx

Pore Favor

Salicylic acid, zinc oxide, niacinamide and urea; strengths not published in the lineup

Compounded topical
Pigmentation06

Musely

The Spot Cream

Variants include hydroquinone 6% or 12%; an HQ-free option uses azelaic acid 17% and tranexamic acid 4%. Other ingredients vary.

Compounded prescription
Fine lines07

Musely

The Anti-Aging Cream

Tretinoin 0.025%, 0.05% or 0.1%, with niacinamide and hyaluronic acid

Compounded prescription
Pigmentation09

Musely

The Spot Pill

Tranexamic acid 225 mg in the current support-center description

Compounded prescription
Pigmentation10

Musely

The Spot Peel

BOOST lists azelaic acid 20% and tretinoin 0.01%; BURST lists hydroquinone 12% and tretinoin 0.01%. Supporting ingredients differ.

Compounded prescription
Eye area11

Musely

The Eye Serum

Smooth 2.0: tretinoin 0.001%, caffeine 1%, hyaluronic acid 2%, niacinamide 2%, bisabolol 2% and exosomes; Smooth+Bright adds hydroquinone 3%.

Compounded prescription
Fine lines12

Musely

The Neck Cream

Lines: tretinoin 0.025%; Lines + Spots: tretinoin 0.01% and hydroquinone 8%. Both list additional ingredients and exosomes.

Compounded prescription
Pigmentation13

Musely

The Body Cream

Vanish: hydroquinone 12%, tretinoin 0.01%, glycolic acid 1%; Fade omits hydroquinone and lists glycolic acid 6%. A KP variant is also documented.

Compounded prescription
Pigmentation14

Musely

The Private Cream

Hydroquinone variants at 3%, 6% and 12%; TENDER instead lists tranexamic acid 6%. Niacinamide 2% accompanies the listed formulas.

Compounded prescription
Acne15

Musely

The Acne Cream

Zap lists tretinoin 0.015%, clindamycin 0.75%, niacinamide 4% and azelaic acid 2%; individual prescriptions may differ.

Compounded prescription
Other skin concerns16

Musely

The KP Cream

Clear: urea 35%, salicylic acid 2.5%, tretinoin 0.07%; Clear+ adds triamcinolone 0.04%; Classic uses a different diclofenac/tretinoin/tacrolimus blend.

Compounded prescription
Rosacea17

Musely

The Rosacea Cream

Red: ivermectin 1%, metronidazole 1%, niacinamide 4%; Blush: azelaic acid 17%, niacinamide 2%.

Compounded prescription
Rosacea18

Musely

The Red Rescue

Oxymetazoline 0.88%; hydrocortisone 1% may be added

Compounded prescription
Rosacea19

Musely

The Rosacea Pill

Doxycycline, described in the support center as starting at 56 mg

Compounded prescription
Rosacea20

Musely

The Red Set

Rosacea Mask: sulfur 3% and sodium sulfacetamide 9%; Rosacea Cream: Red or Blush variant

Compounded prescription
Firmness21

Musely

The Cell Repair Serum

Sirolimus (rapamycin) 0.0125% with iPSC-derived exosomes; X and X++ list different exosome quantities

Compounded prescription
Firmness22

Musely

The Peptide Serum

Renew lists copper peptide 3%, metformin 1%, bisabolol 1% and panthenol 1%

Compounded prescription
Other skin concerns23

Musely

The Skin Pill

Inner Repair lists methylene blue 1.5 mg, glutathione 500 mg and Polypodium leucotomos 500 mg

Compounded prescription
Acne24

Curology

Custom Formula Rx

Up to three clinician-selected ingredients; the individual prescription specifies the combination and strengths

Compounded topical
Fine lines25

Curology

HydroTret Rx

Potential ingredients include tretinoin, dexpanthenol, niacinamide and azelaic acid; a tretinoin-free version is also described

Compounded topical
Acne26

Curology

DayPrime Rx

Three selected actives from a menu including azelaic acid, clindamycin, niacinamide, zinc pyrithione, salicylic acid and dexpanthenol

Compounded topical
Acne27

Curology

Body Cleanse Rx

Provider-selected sulfacetamide, zinc pyrithione and salicylic acid are listed as potential actives

Compounded topical
Acne28

Curology

Deep Cleanse Rx

Prescription facial cleanser; full selected ingredient specification not verified on the pricing page

Compounded topical
Fine lines29

Agency

Night Renew Rx

Potential tretinoin, estriol, azelaic acid and niacinamide; not every formula contains tretinoin

Compounded topical
Firmness30

Agency

Day Defender Rx

Vitamin C (L-ascorbic acid), resveratrol, green tea extract and niacinamide are listed as possible ingredients

Compounded topical
Firmness31

Agency

Cell Repair Rx

Rapamycin (sirolimus) and resveratrol; individual concentrations require confirmation

Compounded topical
Pigmentation32

Agency

Dark Spot Rx

Potential hydroquinone, azelaic acid, kojic acid, green tea extract, resveratrol and hydrocortisone; hydroquinone-free variants exist

Compounded topical
Eye area33

Agency

Eye Revive Rx

Potential tretinoin, caffeine, dexpanthenol, green tea extract and glycerin; not all variants contain tretinoin

Compounded topical
Eye area35

Dear Brightly

Rx Eye Serum

Tretinoin, vitamin C, caffeine and green tea extract; tailored strength

Compounded topical
Acne36

Dear Brightly

Rx Hormonal Acne Serum

Tretinoin, niacinamide, spironolactone and clindamycin; tailored strengths

Compounded topical
Fine lines37

Likeness Rx

Fine Line Cream

Tretinoin 0.05%, niacinamide and vitamin C

Compounded topical
Mature skin38

Likeness Rx

Estrogen Face Cream

Estriol 0.3%, vitamin C 5%, hydrolyzed hyaluronic acid 0.5%

Compounded topical
Pigmentation39

Likeness Rx

Dark Spot Cream

Hydroquinone 6%, kojic acid 6% and niacinamide

Compounded topical
Firmness40

Likeness Rx

Firming Cream

Copper peptide (GHK-Cu) 2%; complete base not published

Compounded topical
Acne41

Likeness Rx

Clear Skin Cream

Salicylic acid, zinc oxide, niacinamide and urea; concentrations not fully stated

Compounded topical
Mature skin42

Alloy

M4 Face Cream Rx

Estriol; confirm the individual concentration and base

Compounded topical
Mature skin44

Alloy

M4 Face Serum Rx

Estriol and peptides; hyaluronic acid is named in the skincare catalog

Compounded topical
Rosacea49

Alloy

Rosacea Face Cream Rx

Azelaic acid, metronidazole and ivermectin; confirm exact strengths

Compounded topical
Fine lines52

Strut Health

Tretinoin Cream

Tretinoin cream in 0.025%, 0.05% or 0.1% strengths

Manufactured prescription
Eye area53

Strut Health

Eye Cream

Tretinoin, tacrolimus, caffeine, niacinamide, bisabolol and vitamin C; copper-peptide base described

Compounded topical
Fine lines54

Strut Health

Neck Cream

Tretinoin, lactic acid, caffeine, niacinamide and sodium hyaluronate in a copper-peptide base

Compounded topical
Fine lines55

Strut Health

Anti-Aging Formula

Tretinoin, niacinamide, lactic acid and sodium hyaluronate

Compounded topical
Firmness56

Strut Health

Brightly Formula

Vitamin C, panthenol, sodium hyaluronate, acetyl hexapeptide and vitamin E

Compounded topical
Pigmentation57

Strut Health

Melasma Formula

Hydroquinone, hydrocortisone, kojic acid and tretinoin

Compounded topical
Rosacea58

Strut Health

Rosacea Formula

Possible azelaic acid, oxymetazoline, metronidazole and ivermectin; the selected blend varies

Compounded topical
Other skin concerns59

Strut Health

Scar Formula

Triamcinolone, levocetirizine and vitamin C in a silicone scar-gel preparation

Compounded topical
Fine lines60

Strut Health

Flawless Combo

Separate Brightly and Anti-Aging formulas; vitamin C blend plus a tretinoin blend

Compounded topical bundle
Acne61

Skin Medicinals

Acne Compound

Tretinoin, azelaic acid and niacinamide are listed options; prescription varies

Compounded topical
Fine lines62

Skin Medicinals

Anti-Aging Compound

Tretinoin with clinician-selected supportive ingredients such as niacinamide and sodium hyaluronate

Compounded topical
Rosacea63

Skin Medicinals

Rosacea Compound

Metronidazole, ivermectin and azelaic acid listed; strengths require the prescription

Compounded topical
Pigmentation64

Skin Medicinals

Hyperpigmentation Compound

Hydroquinone options described at 4%, 8% and 12%; other formula details require confirmation

Compounded topical
Other skin concerns65

Skin Medicinals

Wart Paste

Clinician-selected salicylic acid and fluorouracil (5-FU) strengths

Compounded topical
Other skin concerns66

Skin Medicinals

Inflammatory Skin Compound

Clinician-selected anti-inflammatory ingredients; no single formula established by the condition page

Compounded topical
Acne68

Hims

Customized Acne Cream

Provider-selected blend; safety information names tretinoin, clindamycin, niacinamide and azelaic acid

Compounded topical
Fine lines69

Hers

Anti-Aging Rx Cream

Tretinoin, niacinamide and azelaic acid; strengths determined by the provider

Compounded topical
Acne70

Hers

Acne Cream

Tretinoin, niacinamide, azelaic acid and clindamycin; individual strengths require confirmation

Compounded topical
Fine lines71

RedBox Rx

Tretinoin Cream

Tretinoin cream 0.025%, 0.05% or 0.1%; manufacturer confirmed at dispensing

Manufactured prescription
Acne72

Obagi

Tretinoin Cream and Gel

Prescription tretinoin cream and gel; available strengths vary by dosage form

Manufactured prescription
Fine lines73

Nurx

Tretinoin Cream

Tretinoin 0.025%, 0.05% or 0.1% cream

Manufactured prescription
Fine lines75

Nurx

ReviveRx Cream

Azelaic acid 10%, niacinamide 4%, tretinoin 0.025%, 0.05% or 0.1%; supportive base ingredients

Compounded topical
Pigmentation76

Nurx

Dark Spots Formula

Azelaic acid 6%, kojic acid 6%, hydroquinone 4%, hydrocortisone 1%, tretinoin 0.05%

Compounded topical
Acne82

Nurx

Minocycline

Minocycline HCl; prescribed dose and formulation vary

Oral prescription
Acne83

Nurx

Doxycycline Hyclate

Doxycycline hyclate; exact dose and course are prescribed individually

Oral prescription
Rosacea88

Nurx

Azithromycin

Azithromycin 250 mg listed in the rosacea treatment menu

Oral prescription
Acne91

Cabtreo

Triple Combination Gel

Clindamycin phosphate 1.2%, adapalene 0.15%, benzoyl peroxide 3.1%

Manufactured prescription
Pigmentation98

Tri-Luma

Triple Combination Cream

Fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%

Manufactured prescription
Acne105

Retin-A

Tretinoin Cream and Gel

Tretinoin cream or gel; strength depends on the prescribed dosage form

Manufactured prescription
Acne106

Retin-A Micro

Tretinoin Gel

Tretinoin microsphere gel in 0.04%, 0.06%, 0.08% or 0.1% strengths

Manufactured prescription
Acne108

Tazorac

Tazarotene Cream

Tazarotene cream 0.05% or 0.1%; indication depends on strength

Manufactured prescription
Other skin concerns110

Musely

The Facial Hair Cream

Eflornithine 6% and DMSO 10%; the prescriber may omit an ingredient

Compounded topical
Acne111

Curology

AM to PM Acne Routine

DayPrime Rx plus Custom Formula Rx; each has its own individualized ingredients

Compounded topical bundle
Mature skin113

Alloy

Head to Toe Set

M4 Face Cream Rx, M4 Eye Cream Rx and M4 Body Treatment Rx

Compounded topical bundle
Mature skin114

Alloy

Glow and Go Set

M4 Face Cream Rx, M4 Face Serum Rx and M4 Eye Cream Rx

Compounded topical bundle
Fine lines116

Alloy

Power Pair

M4 Face Cream Rx plus Tretinoin Face Cream Rx

Compounded topical bundle
Mature skin117

Likeness Rx

The Night Set

Estrogen Face Cream plus Fine Line Cream

Compounded topical bundle